Wednesday 12 December 2012

Article: Tools for mapping high-throughput sequencing data


Tools for mapping high-throughput sequencing data
http://bioinformatics.oxfordjournals.org/content/28/24/3169.short?buffer_share=69a0b&rss=1

Motivation: A ubiquitous and fundamental step in high-throughput sequencing analysis is the alignment (mapping) of the generated reads to a reference sequence. To accomplish this task, numerous software tools have been proposed. Determining the mappers that are most suitable for a specific application is not trivial.

Results: This survey focuses on classifying mappers through a wide number of characteristics. The goal is to allow practitioners to compare the mappers more easily and find those that are most suitable for their specific problem.

Availability: A regularly updated compendium of mappers can be found athttp://wwwdev.ebi.ac.uk/fg/hts_mappers/.


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